Feasibility of a randomized trial on adjuvant radio-iodine therapy in differentiated thyroid cancer

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Feasibility of a randomized trial on adjuvant radio-iodine therapy in differentiated thyroid cancer.

BACKGROUND Justification for adjuvant radio-iodine (I-131) therapy in differentiated thyroid cancer (DTC) is purely based on retrospective data. This is true for ablative therapy and even more so for high-dosage adjuvant schedules. Randomized trials on the latter application are considered impossible due to anticipated formidable sample sizes required in a disease with an overall excellent prog...

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Thyroid hormone replacement one day before 131I therapy in patients with well-differentiated thyroid cancer

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ژورنال

عنوان ژورنال: Clinical Endocrinology

سال: 2003

ISSN: 0300-0664

DOI: 10.1046/j.1365-2265.2003.01738.x